Structural Genomics explains 3D Structure of each protein encoded by a given genome. This approach allows a high-throughput technique of structure determination by a combination of experimental and modelling approaches. The principle difference between Genomics and structural prediction is that structural genomics tries to see the structure of every protein encoded by the genome instead of focussing on one specific protein. Protein function depends on 3D structure and these structures are extremely preserved sequences. Thus high-throughput structure determination strategies have potential to tell our understanding of protein functions. This additionally has potential implications on Drug discovery and Protein Engineering.
- Track 1-1 De-novo Method
- Track 2-2 Ab-initio Modelling
- Track 3-3 Sequence Based Modelling
- Track 4-4 Threading
- Track 5-5 Protein Structure Initiative